Quorumdent ™
MICROBIOME
World’s First! The Innovative Toothpaste Formula
Quorum Sensing Technology, inhibiting Harmful Bacteria
Application of the QSI Galacto 90 ® Inhibitor

Quorumdent ™
MICROBIOME
World’s First! The Innovative Toothpaste Formula
Quorum Sensing Technology, inhibiting Harmful Bacteria
Application of the QSI Galacto 90 ® Inhibitor

An innovative breakthrough in decay prevention
QuorumdentTM is a unique hygiene product of a new generation, created on the basis of innovative patented technology. The essence of the technology lies in the use of a substance – QSI Galacto 90® auto-inhibitor that blocks the formation of a bacterial film in the oral cavity. Such biofilms protect the pathogenic bacteria that cause decay from the effects of any
means of prevention.
QuorumdentTM toothpaste does not contain harmful components:
- Now without fluoride,tooth decay&gum disease can be strongly prevented !
- QuorumSensing Inhibiting technology is a breakthrough technology that preserves only
beneficial bacteria and inhibits bad bacteria without indiscriminate sterilzation to improve
oral health system.
Inhibition of Quorumsensing1 (Quorum Sensing) – a revolutionary technology in dentistry
Bacteria are able to communicate with each other. This phenomenon is called “Quorum Sensing”. Communication occurs through special moleculesautoinducers and receptors to them, which are present in the bacteria themselves. After reaching a high concentration, the bacteria become aggressive to the human body. For this purpose, they form biofilms on the surface of the body or mucous membranes. Prevention of formation of such biofilms is “Suppressing the Sense of Quorum.” The Quorum Sensing Inhibition Technology uses an auto inhibitor substance, which is similar to the particles that bacteria use to communicate. An auto inhibitor binds to receptors of bacteria and while they are unable to recognize similar types of bacteria and create biofilms. 1 Quorum-Sensing, “Sensing of Quorum” – a scientific phenomenon. At the International Scientific Library PubMed.gov, there are about 10,000 Quorum Sensing researches.
Understanding of the role of oral microflora and controlling its
balance is the first step to maintaining oral health system
Our organism, including the oral cavity, is inhabited by millions of bacteria. The number of microorganisms in the oral cavity, both in terms of the number of species and the density of microbial contamination, is lagging behind to the large intestine. Almost 700 species of microorganisms are constantly present in the oral cavity (Journal of Bacteriology).
The bacterial microflora of the oral cavity forms a structure that covers the teeth, dentists call it plaque or dental biofilm. The process of biofilm formation begins immediately after you brush your teeth. Pathogenic bacteria are found in plaque. And in a short time, they begin to actively grow and multiply, forming a biofilm. Once in the biofilm, the bacteria begin to work together. Due to their commonality, bacteria become more resistant to antibiotics and the body’s defense systems.
It is very important to maintain the balance of the oral microflora. The imbalance of different types of bacteria creates conditions for excessive reproduction of pathogenic bacteria, playing a leading role in development of a number of diseases.
The main thing is to avoid shifting the balance in any direction favorable for the
development of diseases.

Understanding of the role of oral microflora and controlling its
balance is the first step to maintaining oral health system
Our organism, including the oral cavity, is inhabited by millions of bacteria. The number of microorganisms in the oral cavity, both in terms of the number of species and the density of microbial contamination, is lagging behind to the large intestine. Almost 700 species of microorganisms are constantly present in the oral cavity (Journal of Bacteriology).
The bacterial microflora of the oral cavity forms a structure that covers the teeth, dentists call it plaque or dental biofilm. The process of biofilm formation begins immediately after you brush your teeth. Pathogenic bacteria are found in plaque. And in a short time, they begin to actively grow and multiply, forming a biofilm. Once in the biofilm, the bacteria begin to work together. Due to their commonality, bacteria become more resistant to antibiotics and the body’s defense systems.
It is very important to maintain the balance of the oral microflora. The imbalance of different types of bacteria creates conditions for excessive reproduction of pathogenic bacteria, playing a leading role in development of a number of diseases.
The main thing is to avoid shifting the balance in any direction favorable for the
development of diseases.
An innovative product for the prevention and hygiene
The modern individual has a low mineralization of teeth. Reasons being: milk and
cottage cheese contain less and less calcium, and consumption of sweets is growing. Pathogenic bacteria, concentrated in a soft plaque, destroy the crown of the tooth in 10-15 days.
Most toothpastes do not have a directed action to block the bacterial film. Therefore, their effectiveness for the preservation of teeth is very low.
The intensity and prevalence of decay and gum disease in the population is very high. According to WHO, the incidence of decay in different countries and among different populations ranges from 80% to 98%. In the latest two decades, there has been a trend of increasing morbidity among children, especially in economically developed countries, and by the age of 6-7, 80-90% of children have decay of different depths (Source: Scientific Journal “Fundamental Research”)

An innovative product for the prevention and hygiene
The modern individual has a low mineralization of teeth. Reasons being: milk and
cottage cheese contain less and less calcium, and consumption of sweets is growing. Pathogenic bacteria, concentrated in a soft plaque, destroy the crown of the tooth in 10-15 days.
Most toothpastes do not have a directed action to block the bacterial film. Therefore, their effectiveness for the preservation of teeth is very low.
The intensity and prevalence of decay and gum disease in the population is very high. According to WHO, the incidence of decay in different countries and among different populations ranges from 80% to 98%. In the latest two decades, there has been a trend of increasing morbidity among children, especially in economically developed countries, and by the age of 6-7, 80-90% of children have decay of different depths (Source: Scientific Journal “Fundamental Research”)
Why Quorumdent™?
– Quorumdent technology is developed by the Research Institute of Seoul
National University (South Korea). The essence of the technology lies in the use of a substance – an auto-inhibitor that blocks formation of a bacterial film in the oral cavity. Modern medicine is actively developing substances that inhibit biofilms.
Scientists obtained the substance QSI Galacto90® from natural milk specifically for Quorumdent.
– Quorumdent™ toothpaste inhibits harmful bacteria in the mouth by 80% and
increases the number of beneficial bacteria by 29.28%. Thus, a healthy oral
microflora is maintained. With daily use of Quorumdent toothpaste, biofilm or plaque
does not have time to form, whereas plaque is a breeding ground for bacteria.
– Quorumdent™ toothpaste does not contain harmful components: without
fluoride, without preservatives, without synthetic in surface-active substance (SSAS).
Composition of the toothpaste includes 100% ingredients of natural origin.
– Quorumdent™ toothpaste supports healthy Microflora of the oral cavity. It is
recommended for daily use in children, adolescents, adults and the elderly.
– Quorumdent™ toothpaste will help in the home prevention of decay, both in
children and adolescents, and in adults..

Why Quorumdent™?
– Quorumdent technology is developed by the Research Institute of Seoul
National University (South Korea). The essence of the technology lies in the use of a substance – an auto-inhibitor that blocks formation of a bacterial film in the oral cavity. Modern medicine is actively developing substances that inhibit biofilms.
Scientists obtained the substance QSI Galacto90® from natural milk specifically for Quorumdent.
– Quorumdent™ toothpaste inhibits harmful bacteria in the mouth by 80% and
increases the number of beneficial bacteria by 29.28%. Thus, a healthy oral
microflora is maintained. With daily use of Quorumdent toothpaste, biofilm or plaque
does not have time to form, whereas plaque is a breeding ground for bacteria.
– Quorumdent™ toothpaste does not contain harmful components: without
fluoride, without preservatives, without synthetic in surface-active substance (SSAS).
Composition of the toothpaste includes 100% ingredients of natural origin.
– Quorumdent™ toothpaste supports healthy Microflora of the oral cavity. It is
recommended for daily use in children, adolescents, adults and the elderly.
– Quorumdent™ toothpaste will help in the home prevention of decay, both in
children and adolescents, and in adults..
Benefits of the toothpaste

Excellent teeth whitening effect without hydrogen peroxide

Without fluoride, prevents gum disease and decay

Removes bad breath

Improves oral hygiene system

100% natural components

Reliable protection against gum disease
Composition of the toothpaste
Silicon dioxide – Main ingredient (abrasive), fine particle of dental – type silica
Tocopherol acetate – Main ingredient (Vitamin E), Gum wound healing.
Pyridoxine hydrochloride – Main ingredient (Vitamin B6), prevention of gum disease
Vegetable glycerin – Plant extract, toothpaste’s viscosity and moisture control
Sodium alginate – Plant extract, viscosity control**
Galactose – Natural sweetener, milk ingredient, quorum sensing inhibitor
Ribose – Natural sweetener, safe ingredient created in the body
Calendula extract – Calendula extract, antibacterial and soothing effect
Sodium menthyl cocoyl taurat – Coconut oil ingredient, natural surfactant
Spearmint oil – Natural fragrance, plant extract, flavoring agent
L-Menthol – Natural menthol extracted from plant, flavoring agent
Titanium dioxide – Edible materials used in coffee whipping cream, brighteners
Purified water – Distilled and sterilized water
The task of research center and specialists of “Quorumdent”
Oral health is one of the main indicators of overall health, well-being and quality of life. The World Health Organization defines oral health as: “a condition characterized by the absence of chronic oral and facial pain, oral and throat cancers, oral infections and ulcers, periodontal(gum) diseases, decay, tooth loss, and other diseases and health disorders that limit a person’s ability to bite, chew, smile, and
speak, and their psychosocial well-being.” WHO annually conducts global oral health programmes,
and WE would like that as many people as possible receive information and explanatory
materials on the importance of oral health, importance of balancing the microflora of the oral
cavity – this is the first step to strengthening the immune system. And they make the right
decision in choosing oral hygiene products
The “Quorumdent” team cares about the health of the oral cavity
Experiments
- Use of D-galactose to regulate biofilm growth of oral streptococci

- Inhibiting effect of harmful bacteria
1.An experiment on suppression of S. mutans biofilms
(before and after use Quorumdent)
2, Experiment on S. oralis biofilm
(before and after using Quorumdent)

*Experiment shows that the use of toothpaste inhibits the formation of S.mutans biofilm, harmful bacteria in the mouth by up to 80%. And S.oralis, beneficial bacteria are well preserved and even increase by 29.28%
Strong teeth whitening effect

Toothpaste uses a new method of increasing absorption of a pigment without the
use of hydrogen peroxide. Pigments from coffee, curry, etc. formed between teeth
are absorbed and removed, which returns whiteness of teeth.
You can find that the pigment left on the cleavage (B) and dent of the tooth and
yellowing is gently removed after using toothpaste Quorumdent.
Composition of the toothpaste
Silicon dioxide – Main ingredient (abrasive), fine particle of dental – type silica
Tocopherol acetate – Main ingredient (Vitamin E), Gum wound healing.
Pyridoxine hydrochloride – Main ingredient (Vitamin B6), prevention of gum disease
Vegetable glycerin – Plant extract, toothpaste’s viscosity and moisture control
Sodium alginate – Plant extract, viscosity control**
Galactose – Natural sweetener, milk ingredient, quorum sensing inhibitor
Ribose – Natural sweetener, safe ingredient created in the body
Calendula extract – Calendula extract, antibacterial and soothing effect
Sodium menthyl cocoyl taurat – Coconut oil ingredient, natural surfactant
Spearmint oil – Natural fragrance, plant extract, flavoring agent
L-Menthol – Natural menthol extracted from plant, flavoring agent
Titanium dioxide – Edible materials used in coffee whipping cream, brighteners
Purified water – Distilled and sterilized water
The task of research center and specialists of “Quorumdent”
Oral health is one of the main indicators of overall health, well-being and quality of life. The World Health Organization defines oral health as: “a condition characterized by the absence of chronic oral and facial pain, oral and throat cancers, oral infections and ulcers, periodontal(gum) diseases, decay, tooth loss, and other diseases and health disorders that limit a person’s ability to bite, chew, smile, and
speak, and their psychosocial well-being.” WHO annually conducts global oral health programmes,
and WE would like that as many people as possible receive information and explanatory
materials on the importance of oral health, importance of balancing the microflora of the oral
cavity – this is the first step to strengthening the immune system. And they make the right
decision in choosing oral hygiene products
The “Quorumdent” team cares about the health of the oral cavity
Experiments
- Use of D-galactose to regulate biofilm growth of oral streptococci

- Inhibiting effect of harmful bacteria
1.An experiment on suppression of S. mutans biofilms
(before and after use Quorumdent)

2, Experiment on S. oralis biofilm
(before and after using Quorumdent)

*Experiment shows that the use of toothpaste inhibits the formation of S.mutans biofilm, harmful bacteria in the mouth by up to 80%. And S.oralis, beneficial bacteria are well preserved and even increase by 29.28%